Mama:
The situation you describe has been known to make even men of the clergy utter discouraging words!
doctah and toverman (I just love his technical terms..."a real booger..."!) give good counsel. Trial and error! If you are attempting to pose them, get them in the same plane, or nearly so, compact group. Threaten them with grounding till they are 25!

(Not the dog, he wouldn't understand.)
Set 'em up, and shoot fast! Watch the preflash...dogs, cats, children, and my daughter in law will react to that faster than you would ever believe, and close their eyes.
Remember, DOF extends from ~1/3 in front of the subject to ~2/3 behind. Focus accordingly. Good luck!