You can't keep ProPhoto out of the mix if you want the best work.
I would never work in any color space but
ProPhoto RGB from raw conversion and editing and not do any color space conversion until the last. As for a lab that requires sRGB, I would for another lab, one which provides ICC profiles for their printers and papers and can handle larger color gamuts. What ICC profile are you using now? As for printing your own, I do that to have control and print directly from ProPhoto to an Epson R1800 with good ICC profile, Adobe photoshop doing all the color mangment and never convert to sRGB except for web images.